PB Serum
Localised Concerns. Targeted Enzyme Assessment.
Doctor-assessed recombinant enzyme formulations for selected fatty fibrosis and tissue-quality concerns, with limited and indication-specific human evidence.
Type
Recombinant enzyme system with HA vehicle, PB Serum HA 2.0 Medium + High
Main Focus
Selected fibrosis, contour or tissue quality
Duration
Doctor-confirmed only; no standard quote
Course
Individualised after product IFU review
What It Is
PB Serum HA 2.0 is a product range involving recombinant enzymes, with separate Medium and High variants used by the clinic. Your exact concern determines whether enzyme treatment is appropriate.
Main Use
The manufacturer positions Medium for localized fatty fibrosis, with human evidence specifically for Medium cellulite treatment remaining small. High is positioned for certain flaccid or atrophic fibrosis and firmness concerns; it has not been proved universally stronger.
Main Benefits
A 2024 case series reported improvement in four patients with thigh cellulite using Medium. A separate submental study used a different enzyme mixture and cannot be equated to HA 2.0.
How It Works
This is not a weight-loss treatment. General weight loss and focal contour concerns are different medical goals, and no guaranteed fat loss can be promised.
Who It Suits
Adults whose localized tissue concern and medical history support a specific plan, with realistic outcomes and risk counselling.
Treatment Duration
Doctor-confirmed only; there is no standard quote for timing.
Sessions Needed
There is no justified universal HA 2.0 Medium or High course across all body sites; your doctor will discuss current product instructions.
Results Timeline
Preliminary four-patient Medium evidence exists for thigh cellulite, but certainty is low. Evidence for double chin, arms and abdomen uses different or product-specific outcomes that have not been established.
Results Longevity
No published duration data for PB Serum HA 2.0 results are available; a fixed timeframe cannot be responsibly quoted.
Downtime
Swelling, bruising, pain, lumps, infection and potential allergic or contour reactions.
Side Effects
Swelling, bruising, pain, lumps, infection and potential allergic or contour reactions.
Alone Or Combined
A doctor may separate a laxity treatment from a fibrosis goal; benefit and timing of exact combinations are unproven.
Doctor-assessed recombinant enzyme formulations for selected fatty fibrosis and tissue-quality concerns, with limited and indication-specific human evidence.
Purposeful Combinations
Sunny RF
Only for separately identified tissue laxity, not confirmed enzyme synergy.
Tightan II HIFU
For selected depth/firmness goals after independent examination.
Ultherapy PRIME
Accessible for suitable facial laxity; no direct PB HA2.0 protocol evidence.
Skin analysis / clinical photos
Objective area, circumference/contour and skin-quality assessment where relevant.
Lifestyle and weight care
For broader weight goals; not a substitute for treatment-specific evidence.
Commonly Asked
Reviewed by Dr. Dinesh Kanasen (MMC 43953) · Last updated 23 October 2026
The right treatment begins with a proper diagnosis.
At Dr.D Signature Clinic, we discuss PB Serum only after assessing your skin concern, medical history, product-specific evidence, realistic risks and alternatives. A combination is recommended only when it serves a clear separate goal. Book a skin assessment to build a treatment plan around what your skin actually needs.
Curious if PB Serum is right for you?
Every treatment plan starts with a doctor-led assessment of your skin, goals and medical history.