PN / PDRN Treatments

They're a category of doctor-administered polynucleotide injectables used to support skin repair, resilience and overall skin quality rather than add facial volume. We offer Plinest, Plenhyage, Rejuran Healer and Rejuran HB Plus; your doctor confirms which product suits your skin.

They differ in origin (fish-derived Plinest and Plenhyage from Italy, salmon-derived Rejuran from Korea), strength and added ingredients, for example Rejuran HB Plus also contains hyaluronic acid and lidocaine. No verified head-to-head trial establishes an overall winner, so your doctor matches the product to your skin and goals.

Most products use topical numbing cream before the intradermal injections, though some discomfort can still remain. Comfort varies by product and treatment area.

Mild swelling is generally expected to settle within about 6-24 hours as a clinic estimate, though redness, bumps or bruising can last several days depending on the product and area.

Most PN courses start with around 3 sessions spaced 3-4 weeks apart, with your doctor reviewing progress before deciding on further treatment.

PN treatments aren't primarily indicated for pigment disorders or established acne scars; these usually need a separately diagnosed, targeted treatment.

Yes, in selected patients. Each product's own combination guidance is set out on its page, and your doctor plans safe sequencing and timing.